13, Lu C*, Wang W, Fu YX*. (2026). Opportunities and challenges of targeting cGAS-STING in cancer. Nature Reviews Cancer.
12, Huang H, Du L, Su R, Li Z, Shao Y, Yuan Y, Wang C, Lu C, He Y, He H, Zhang C. (2024). Albumin-based co-loaded sonosensitizer and STING agonist nanodelivery system for enhanced sonodynamic and immune combination antitumor therapy. J Control Release,14(1):5246.
11, Huang Y#, Lu C#, Wang H, Gu L, Fu YX*, Li GM*. (2023). DNAJA2 deficiency activates cGAS-STING pathway via the induction of aberrant mitosis and chromosome instability. Nature Communications,14(1):5246.
10, Cai Y, Zhang A, Lu C*. (2022). Precision intervention of cell type-specific targeting is required for future cancer immunotherapy. Medical Review, 2(6), 553-554.
9, Liu L, Chen J, Zhang H, Ye J, Moore C, Lu C, Fang Y, Fu YX*, Bo Li*. (2022). Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated antitumor immunity. Nature Cancer, 1-16
8, Lu C, Guan J, Lu S, et al.. (2021).DNA sensing in mismatch repair-deficient tumor cells is essential for anti-tumor immunity. Cancer Cell, 39(1), pp.96-108.
A highly citated paper by the Web of Science. This paper is elected by European Association for Cancer Research as ‘The EACR's Top 10 Cancer Research Publications' in the year 2020. Meanwhile, it is highly evaluated by Professor Andrés Cervantes, current president of the European Society for Medical Oncology (ESMO) (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921503/). This paper is previewed by Cancer Cell (https://www.cell.com/cancer-cell/fulltext/S1535-6108(20)30664-4), meanwhile highlighted by Science Signaling (https://stke.sciencemag.org/content/14/666/eabg5661.full)
7, Guan J#, Lu C#, Jin Q, et al.. (2021). MLH1 deficiency-triggered DNA hyperexcision by exonuclease 1 activates the cGAS-STING pathway. Cancer Cell, 39(1), pp.109-121. Faculty opinions by Alejandro Schaffer (https://facultyopinions.com/article/739232243?key=yjSJqzLkacyu7KY)
6, Zhang A, Ren Z, Tseng KF, Liu X, Huiyu Li, Lu C, Cai Y, Minna J, Fu YX. (2021). Dual targeting of CTLA-4 and CD47 on Treg cells promotes immunity against solid tumors. Science Translational Medicine, 13(605), eabg8693.
5, Li H.-D., Lu C, Zhang H, et al.. (2020). A Pole P286R mouse model of endometrial cancer recapitulates high mutational burden and immunotherapy response. JCI insight, 5(14).
4, Han C, Liu Z, Zhang Y, Shen A, Dong C, Zhang A, Moore C, Ren Z, Lu C, Cao X, Zhang CL, Qiao J*, Fu YX*. (2020). Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling. Nature immunology, 21(5), 546-554.
3, Suresh S, Chen B, Zhu J, Golden R, Lu C, Evers B, ... O'Donnell K. (2020). eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer. Nature Cancer, 1(5), 533-545.
2, Liu Z, Han C, Dong C, Shen A, Hsu E, Ren Z, Lu C, Liu L, Zhang A, Timmerman C, Pu Y, Wang Y, Chen M, Qiao J, Fu YX. (2019). Hypofractionated EGFR tyrosine kinase inhibitor limits tumor relapse through triggering innate and adaptive immunity. Science immunology, 4(38).
1, Li HD, Cuevas I, Zhang M, Lu C, Alam M, Fu YX, You J, Akbay E, Zhang H, Castrillon D. (2018). Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load. The Journal of clinical investigation, 128(9), 4179-4191.
Lulab publications: google scholar
